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Combined use of two AI algorithms for evaluating embryo quality improves selection of embryos leading to clinical pregnancy

AI Healthcare company Presagen, in collaboration with Ovation Fertility (USA), Flinders Fertility (Australia), Alpha Fertility (Malaysia) and ORM Fertility (USA), presented a recent study of Life Whisperer at the American Society for Reproductive Medicine (ASRM) 2022 Scientific Congress, Oct 2022.

Life Whisperer uses Artificial Intelligence to assess images of IVF patients’ embryos to evaluate their quality, in order to improve IVF outcomes. Life Whisperer comprises two AI algorithms intended to provide insight into different aspects of embryo quality. Life Whisperer Viability AI assesses how likely embryos are to lead to a pregnancy, and Life Whisperer Genetics AI non-invasively assesses embryo genetic integrity.

This international study showed that the combined use of both AI algorithms further reduced the number of cycles needed for patients to achieve a clinical pregnancy compared to viability AI assessment alone.

While each AI algorithm independently provided information on the likelihood of pregnancy, results showed a performance boost in selecting embryos that will lead to pregnancy when using Life Whisperer Genetics AI to pre-select embryos, then ranking the embryos using the Life Whisperer Viability AI.

This study is important for the IVF industry for two reasons. Firstly, it suggests that embryo quality is a function of both viability and genetic integrity, and that these provide overlapping but distinct information regarding pregnancy. Using both AI algorithms together achieves the best results.

Secondly, results show that AI imaging provides an effective approach for evaluating embryo genetic integrity. It is non-invasive, low cost and instant, and may improve outcomes when used with other methods for embryo evaluation and selection.

Download the poster here

Life Whisperer

Life Whisperer is a world-leader in the application of AI in IVF. The Life Whisperer Viability and Genetics AI-based embryo assessment tools are the first to be commercialized in a series of applications that encompass the complete IVF journey. Life Whisperer aims to improve IVF success rates at every point and, as a result, reduce time-to-pregnancy, making IVF more affordable and accessible to patients globally. Life Whisperer is being used in IVF clinics around the world.

Presagen

Presagen is an AI healthcare company that is changing the way clinics, patients, and medical data from around the world are connected through AI. Its platform, The Social Network for Healthcare, connects clinics and patients globally, and enables collaboration and data sharing to create scalable AI healthcare products that are affordable and accessible for all. The decentralized network democratizes the creation of AI products, promotes collaboration through incentives, and protects data privacy and ownership. With a focus on improving Women’s Health outcomes globally, Presagen’s first product, Life Whisperer, is being used by IVF clinics globally to improve pregnancy outcomes for couples struggling with fertility. With a vision of creating the largest network of clinics, patients, and medical data from around the world, Presagen is driving the future of AI Enhanced Healthcare.

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Life Whisperer
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Presagen parent company to Life Whisperer

Published in Human Reproduction by Oxford University Press.

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